Cincinnati is a city in the U.S. state of Ohio and seat of Hamilton County. Settled 1788, the city was located at the north side of the confluence of the Licking River to the Ohio. The city drives the Cincinnati–Middletown–Wilmington combined statistical area, which had a population of 2,172,191 in the 2010 census. With a population of 298,800, Cincinnati holds the third-biggest city proper in Ohio and the 65th-biggest in the United States, is the fastest growing economic power in the Midwestern United States and 28th-biggest metropolitan statistical area in the United States, the biggest in Ohio, being within one day's drive of two-thirds of United States populaces.In the nineteenth century, Cincinnati was an American boomtown in the heart of the country; it rivaled the larger coastal cities in size and wealth. Throughout much of the 19th century, it was listed among the top 10 U.S.